Nifedipine may cause fluid retention (edema) in some patients. Tell your doctor right away if you develop swelling or swelling of your face, arms, hands, calves, or feet; tingling in your hands or feet; or unusual weight gain or loss. Do not stop taking nifedipine without first consulting your doctor.
Will Nifedipine Make You Gain Weight?
Nifedipine Treatment antagonizes weight gain, and increased systemic energy expenditure and lipid oxidation in skeletal muscle. Interestingly, we also observed increased peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC-1α) expression in skeletal muscle of nifedipine-treated eNOS-deficient mice.
What are the most common side effects of nifedipine?
Nifedipine lowers your blood pressure, making it easier for your heart to pump blood around your body.The most common side effects include headache, flushing, constipation, feeling tired, and swollen ankles. These usually improve after a few days of treatment.
What adverse reactions are associated with nifedipine?
The most common adverse reactions include Flushing, peripheral edema, dizziness, headache. The sustained-release formulation was better tolerated than the immediate-release formulation of nifedipine. Allergic reactions, such as itching, hives, and bronchospasm, are relatively rare.
Does nifedipine make you urinate a lot?
rash or itching, urinating more than usual, or. Flushing (warmth/redness/tingling sensation under the skin).
Medications that cause weight gain
17 related questions found
Why stop using nifedipine?
If it lasts for a long time, The heart and arteries may not function properly. This can damage blood vessels in the brain, heart and kidneys, leading to stroke, heart failure or kidney failure. High blood pressure may also increase the risk of heart attack.
When is the best time to take nifedipine?
Capsules are usually taken three to four times a day.Extended-release tablets should be taken once daily on an empty stomach, or 1 hour before or 2 hours after meal. To help you remember to take nifedipine, take it at about the same time each day.
Which medicines should not be taken with nifedipine?
Strong CYP3A inducers such as Rifampicinrifabutin, phenobarbital, phenytoin, carbamazepine, and St. John’s wort reduce the bioavailability and efficacy of nifedipine; therefore, nifedipine should not be used in combination with strong CYP3A inducers such as rifampicin (see Contraindications).
What is a good alternative to nifedipine?
Nisoldipine It appears to be an effective alternative to nifedipine in patients with severe hypertension who are sensitive or resistant to nifedipine.
Should nifedipine be discontinued?
Bayer discontinues its own MR’s nifedipine product — which was sold last year as Adalat Retard — expects three strengths of its Adalat LA extended-release tablet to be out of stock by 2021.
Can I drink coffee with nifedipine?
Because caffeine and nifedipine may contain reaction In terms of intracellular calcium concentration, possible interactions between these drugs on blood pressure and heart rate were examined.
How much does nifedipine lower blood pressure?
Continuous hemodynamic monitoring provides further evidence’2 that nifedipine has a rapid, profound and durable antihypertensive effect.In fact, mean arterial pressure decreased by 21% (mean decrease of 28 mmHg) at 30 minutes compared to the control group, and 16% drop 120 minutes after taking the drug.
Does Nifedipine Cause Anxiety?
Nifedipine has a higher incidence of neurological side effects than other dihydropyridines, including Dizziness and anxietythey write.
Does Nifedipine Cause Depression?
reported two cases of depression associated with the use of the calcium channel blocker nifedipine. In one case, a patient did not respond to nortriptyline treatment following nifedipine. In both cases, Depression resolves after nifedipine discontinuation.
Does Nifedipine Cause Memory Loss?
Generally speaking, Ineffective or even worsened memory observed In combination with nifedipine, diltiazem, verapamil and amlodipine (Skinner et al, 1992; Maxwell et al, 1999; Bachmeier et al, 2011; Paris et al, 2011).
Is nifedipine bad for the kidneys?
Nifedipine can cause a slight increase in the metabolic rate in patients with renal failure, but no dose adjustment is required. has the effect of lowering blood pressure, minor side effects And may improve kidney function in some patients.
Which is better, amlodipine or nifedipine?
Amlodipine is better tolerated than nifedipine, as indicated by the lower incidence of side effects. Therefore, amlodipine has been shown to be an effective and well-tolerated drug for the treatment of mild to moderate hypertension.
How fast does nifedipine work?
Nifedipine (Procardia XL) tablets have extended-release properties, so they are slowly absorbed in the body over time and can Up to 6 hours achieve the « peak » effect. The capsule form (Procardia) works quickly and will start working within 30 minutes.
Why must nifedipine be taken on an empty stomach?
It is best to take this tablet on an empty stomach.If you are taking extended-release tablets, some Tablets may end up in your stool after your body Medicine has been absorbed. This is normal and nothing to worry about.
Does nifedipine lower heart rate?
Nifedipine increases heart rate in patients with ischemic heart disease only during the day, Decreased parasympathetic nerve activity.
What are the 4 worst blood pressure drugs?
Blood Pressure Medications: Know Your Options
- Atenolol. …
- Furosemide (Lasix)…
- Nifedipine (Adalat, Procardia)…
- Terazosin (Hytrin) and Prazosin (Minipress) …
- Hydralazine (Apresoline)…
- Clonidine (Catapres)
Can vitamin C be taken with nifedipine?
no interaction Found between nifedipine and vitamin C. This does not necessarily mean that there is no interaction.
Is it okay to take nifedipine before bed?
In addition, GITS with nifedipine at bedtime reduced the incidence of edema as an adverse event by 91% and the sum of all adverse events by 74% compared to morning dosing (p=0.026).
Is it better to take nifedipine in the morning or at night?
Statistical analysis shows No significant difference between morning and evening dosing. Two patients discontinued the medication due to intolerable side effects (fatigue and muscle cramps, respectively). The other two had mild reversible headaches that did not lead to discontinuation.
Are eggs bad for high blood pressure?
Eggs are also a well-known source of protein and are great for breakfast. Egg whites are especially good for high blood pressure. You can prepare scrambled eggs and add some vegetables.